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Anna Wintour's advice for young scrubs trying to win at fashion: Get fired.
"Everyone should get sacked at least once," she offers. "It forces you to look at yourself [...] It is important to have setbacks, because that is the reality of life. Perfection doesn't exist." This knowledge came from personal experience, specifically Wintour's unceremonious boot from a junior fashion editor job at Harper's Bazaar in 1975.
This and other hot tips (like, "Even if you aren't sure of yourself, pretend that you are, because it makes it clearer for everyone else.") appear in Winners, by Alastair Campbell, an excerpt of which can be found in the Sunday Times right now.